Publications

EN-ACTI2NG Publications 

EN-ACTI2NG publications derived from the research project are under preparation

 

Publications of participating groups

Receptor Pre-Clustering and T cell Responses: Insights into Molecular Mechanisms.
Castro M, van Santen HM, Férez M, Alarcón B, Lythe G, Molina-París C.
Front Immunol. 2014 Apr 30;5:132. doi: 10.3389/fimmu.2014.00132. eCollection 2014. Review.

Cognate peptide-MHC complexes are expressed as tightly apposed nanoclusters in virus-infected cells to allow TCR crosslinking.
Ferez M, Castro M, Alarcon B, van Santen HM.
J Immunol. 2014 Jan 1;192(1):52-8. doi: 10.4049/jimmunol.1301224. Epub 2013 Dec 4.

Models of self-peptide sampling by developing T cells identify candidate mechanisms of thymic selection.
Bains I, van Santen HM, Seddon B, Yates AJ.
PLoS Comput Biol. 2013;9(7):e1003102. doi: 10.1371/journal.pcbi.1003102. Epub 2013 Jul 25.

Increased sensitivity of antigen-experienced T cells through the enrichment of oligomeric T cell receptor complexes.
Kumar R, Ferez M, Swamy M, Arechaga I, Rejas MT, Valpuesta JM, Schamel WW, Alarcon B, van Santen HM.
Immunity. 2011 Sep 23;35(3):375-87. doi: 10.1016/j.immuni.2011.08.010. Epub 2011 Sep 8.