EN-ACTI2NG Publications
Flow cytometry multiplexed method for the detection of neutralizing human antibodies to the native SARS-CoV-2 spike protein.
Horndler L, Delgado P, Abia D, Balabanov I, Martínez-Fleta P, Cornish G, Llamas MA, Serrano-Villar S, Sánchez-Madrid F, Fresno M, van Santen HM, Alarcón B. . EMBO Mol Med. 2021 Mar 5;13(3):e13549. doi: 10.15252/emmm.202013549.
Noncanonical binding of Lck to CD3ε promotes TCR signaling and CAR function.
Hartl FA, Beck-Garcìa E, Woessner NM, Flachsmann LJ, Cárdenas RMV, Brandl SM, Taromi S, Fiala GJ, Morath A, Mishra P, Yousefi OS, Zimmermann J, Hoefflin N, Köhn M, Wöhrl BM, Zeiser R, Schweimer K, Günther S, Schamel WW, Minguet S. Nat Immunol. 2020 Aug;21(8):902-913. doi: 10.1038/s41590-020-0732-3. Erratum in: Nat Immunol. 2021 Jan;22(1):100-101.
Three-dimensional single molecule localization close to the coverslip: a comparison of methods exploiting supercritical angle fluorescence.
Zelger P, Bodner L, Offterdinger M, Velas L, Schütz GJ, Jesacher A. Biomed Opt Express. 2021;12(2):802-822. Published 2021 Jan 12. doi:10.1364/BOE.413018
Aptamers Against Live Targets: Is In Vivo SELEX Finally Coming to the Edge?
Sola, M., Menon, A. P., Moreno, B., Meraviglia-Crivelli, D., Soldevilla, M. M., Cartón-García, F., & Pastor, F
Molecular Therapy-Nucleic Acids. 2020 Sep 21; 192:204. doi: 10.1016/j.omtn.2020.05.025
Inefficient CAR-proximal signaling blunts antigen sensitivity
Gudipati V., Rydzek J., Doel-Perez I., Gonçalves V.DR., Scharf L, Königsberger S., Lobner E., Kunert R., Einsele H., Stockinger H., Hudecek M., Huppa J.B. Nat Immunol. 2020 Aug; 21(8):848-856. doi: 10.1038/s41590-020-0719-0.
Defocused imaging exploits supercritical-angle fluorescence emission for precise axial single molecule localization microscopy.
Zelger P, Bodner L, Velas L, Schütz GJ, Jesacher A. Biomed Opt Express. 2020 Jan 13;11(2):775-790. doi: 10.1364/BOE.375678. Erratum in: Biomed Opt Express. 2020 Sep 08;11(10):5456-5457.
ICOS Costimulation at the Tumor Site in Combination with CTLA-4 Blockade Therapy Elicits Strong Tumor Immunity
Soldevilla MM, Villanueva H, Meraviglia-Crivelli D, Menon AP, Ruiz M, Cebollero J, Villalba M, Moreno B, Lozano T, Llopiz D, Pejenaute Á, Sarobe P, Pastor F. Mol Ther. 2019 Nov 6;27(11):1878-1891. doi: 10.1016/j.ymthe.2019.07.013.
Chimeric antigen receptors designed to overcome transforming growth factor-β-mediated repression in the adoptive T-cell therapy of solid tumors.
Hartley J, Abken H. Clin Transl Immunology. 2019 Jun 22;8(6):e1064. doi: 10.1002/cti2.1064.
Three-dimensional localization microscopy using deep learning.
Zelger P, Kaser K, Rossboth B, Velas L, Schütz GJ, Jesacher Opt Express. 2018 Dec 10;26(25):33166-33179. doi: 10.1364/OE.26.033166.
Additional EN-ACTI2NG publications derived from the research project are under preparation